ATS Xtend™ UV On-/Offline

Get the best of both worlds. Online UV-Vis measuring and offline collection of dissolution samples.

  • FLEXIBILITY - Delivers real-time UV-Vis results and collects samples in tubes, LC vials, or wellplates
  • ONLINE - Single wavelength or multi-components analysis with integrated UV-Vis spectrophotometer
  • FAST - Sample and measure as often as ever 60 seconds in each vessel for multi-timepoint methods
  • COMPARE - Collect measured samples to easily compare your analytical finishes
  • DATA INTEGRITY - Automatically report measured UV-Vis results together with protocolled test conditions
  • COMPLIANT - Fulfills all Pharmacopeia and 21 CFR part 11 requirements for electronic records keeping
  • UV-VIS - Integrate the UV-Vis technology of your choice - double beam or diode array

Automation

Dissolution process steps with a semi-automated UV On-/Offline dissolution testing system.

Highlights

The best of two worlds.

The ATS XtendTM UV On-/Offline combines the efficiency of online UV-Vis measuring with the flexibility of an offline system. Tests with online analysis and offline collection can be alternated without any change-over of tubing. If required, measured samples can also be collected to compare analytical finishes or for other purposes.

Choose your UV-Vis.

Choose between integrating a double beam spectrophotometer or a diode array UV-Vis and perform a full scan in each vessel as often as every 60 seconds. The compact Mettler Toledo® UV7 excels with fast and precise measurements in a wavelength range of 190 - 1100nm. The Specord® offers true double beam UV-Vis technology (CDD) with reference compensation.

Sampling line cleaning.

Equipped with a media selector, your ATS XtendTM automatically replaces withdrawn sampling volumes for delayed release (DR) methods and adds media for pH changes. At the end of a test, the operator can initiate an automated cleaning routine to flush all sampling lines - without having to disconnect any tubing.

Filtration & Collection.

If you collect dissolution samples offline for HPLC / UPLC analysis, fine filtration is required. Configured with powerful CP piston pump technology, the ATS XtendTM pushes through filters with a minimum porosity of 0.2 microns and also handles foaming media with surfactants. Depending on requirements, you can use tip filters, disc filters, and syringe filters - or any combination of the three.

Scalable data management.

Whether operated with q-doc® data management software or WinSOTAX©plus software, all UV-Vis results are reported together with protocolled test conditions. Full compliance with 21 CFR part 11 requirements and segregation of roles, as required by FDA data integrity guidelines, are standard. The modular software structure ensures full scalability - from single workstations to networking multiple systems.

Modules

AT dissolution tester

Xtend™ dissolution bath with flexible sampling & monitoring functions.

Benchtop pump with maintenance-free ceramic piston heads

CP piston pump

Fast and powerful to push through filters and to handle foaming media.

Integrated UV-Vis analysis for immediate dissolution results.

UV7 UV-Vis

Compact and fast diode array spectrophotometer for UV Online.

SAM SR sample manager

Collect dissolution samples in tubes, capped LC vials, and wellplates.

Data management software for all methods, results, and users.

q-doc® software

All your data in one place with built-in 21 CFR part 11 compliance.

Options

Benchtop filter station to automatically change syringe filters.

FS filter station

Automated change of syringe filters for multi-timepoint methods (DR/MR).

WinSOTAX®plus

Dissolution software to manage methods, results, and reports.

MPS media preparation station for manual and semi-automated dissolution testing systems.

MPS media station

Mobile media preparation station to heat, degas and dispense in vessels.

DVC-24 vessel cleaner

Mobile unit to empty and clean vessels of multiple dissolution testers.

Downloads

Downloads

Links