ATS Xtend™ Offline

Automatically withdraw, filter, and collect dissolution samples in tubes, capped LC vials, or wellplates.

  • SAMPLING - Always take samples the same way at reproducible withdrawal positions
  • OFFLINE - Collect samples in glass tubes, capped LC vials, or HPLC / UPLC wellplates
  • METHODS - Program multiple timepoints and automatically replace withdrawn sampling volumes
  • FAST - Timepoint intervals of less than 1 minute possible with powerful piston pump
  • MODIFIED RELEASE - Automatically change filters at defined timepoints for your DR / MR methods
  • FINE FILTRATION - Push through filters with a minimum porosity of 0.2 microns for offline HPLC / UPLC analysis
  • FLEXIBLE - Maintain full flexibility without dedicating your dissolution system to an analytical device

Automation

Dissolution process steps with a semi-automated Offline dissolution testing system.

Highlights

Reproducible sampling.

The ATS XtendTM Offline automates essential steps of your dissolution test - making them highly repeatable. Samples are simultaneously taken from 6-8 vessels, filtered, and collected in tubes, capped LC vials, or wellplates. Standardization of the sampling position, pulling force, volume, timing, and filtration reduces potential sources of variability and makes your testing process more efficient.

More

Multi-purpose media selector.

Perform one-touch sample line cleaning on completion of a test. Simply connect a water tank to the multi-purpose selector of your XtendTM bath and start the automated tube-flushing routine. Up to 3 additional sources can be connected to automatically replace withdrawn sampling volumes during dissolution tests with multiple timepoints or to execute pH changes by adding media.

Highly effective filtration.

XtendTM is built on flexible sampling and filtration. Mimic existing environments when replacing old dissolution testers to ensure comparability of results. Use tip filters or sieves for pre-filtration, disc filters in the suction head, or standard syringe filters. Require fine filtration for your analytical finish? No problem - the powerful CP piston pump can push through filters down to 0.2 microns and also handles foaming media with surfactants. 

Easy to use.

Operators simply select a method on the EasyTouchTM user interface and press START to initiate the dissolution test. In full compliance with the FDA data integrity guidance on segregation of roles, only authorized personnel like supervisors or administrators can modify existing methods or create new recipes. To share methods between multiple systems, the ATS XtendTM can be conveniently networked with data management software.

Individual video monitoring of each dissolution vessel throughout the test

Monitoring dissolution.

Use AutoLiftTM to automatically protocol temperatures inside all 6-8 vessels before test start, when taking samples, or at any point during the test. Additionally, you can record dissolution behavior inside each vessel with CenterViewTM to document that proper procedure has been followed, or more importantly, that a deviation has occurred.

Modules

AT dissolution bath for manual and semi-automated testing.

AT dissolution tester

Xtend™ dissolution bath with flexible sampling & monitoring functions.

Benchtop pump with maintenance-free ceramic piston heads

CP piston pump

Fast and powerful to push through filters and to handle foaming media.

SAM SR sample manager

Collect samples in tubes, capped LC vials, or wellplates for offline analysis.

Options

Benchtop filter station to automatically change syringe filters.

FS filter station

Automated change of syringe filters for multi-timepoint methods (DR/MR).

Syringe pump for semi-automated offline systems.

SP syringe pump

Space-saving pumping module mounted on SAM sample collector.

Data management software for all methods, results, and users.

q-doc® software

All your data in one place with built-in 21 CFR part 11 compliance.

WinSOTAX®plus

Dissolution software to manage methods, results, and reports.

MPS media preparation station for manual and semi-automated dissolution testing systems.

MPS media station

Mobile media preparation station to heat, degas and dispense in vessels.

DVC-24 vessel cleaner

Mobile unit to empty and clean vessels of multiple dissolution testers.

Integrated video monitoring for individual vessels.

CenterView™

Video monitoring of the dissolution process in each individual vessel.

Downloads

Downloads

Links