ATS Xtend™ LC On-/Offline

Automated injection of collected dissolution samples directly into your HPLC / UPLC system.

  • INJECTION - Unattended injection of dissolution samples directly into your liquid chromatography system
  • ERROR PREVENTION - No more time-consuming and error-prone manual re-racking of collected samples
  • TIME - Reduce the time from sampling to injection of filtered samples to an absolute minimum
  • COOLING - Prevent degradation of samples during buffering by adding cooling to your sample manager
  • FILTRATION - Use fine filtration down to 0.2 microns to prevent clogging of your HPLC / UPLC columns
  • INTEGRATION - Flexible integration of different HPLC / UPLC brands and systems possible
  • AUTOMATED - Highly repeatable sampling, filtration, and injection into HPLC / UPLC

Automation

Dissolution process steps with a semi-automated LC On-/Offline dissolution testing system.

Highlights

Automated injection.

Forget about the problems associated with re-racking and manual transfer of dissolution samples. Your XtendTM dissolution system automatically takes samples from all vessels, filters down to a porosity of 0.2 microns, collects filtered samples in the SAM sample manager, and then immediately starts injecting them one by one directly into your HPLC / UPLC chromatography unit.

Flexible filtration.

The ATS XtendTM allows using a wide range of different filters - from tip filters / cannula filters for pre-filtration, to disc filters inside the suction head, and standard 25mm syringe filters. Avoid saturation or clogging for your DR / MR methods and automatically change filters with an integrated filter station.

Parallel processing.

For multi-timepoint tests with delayed release (DR) and modified release (MR) methods, the SAM sample manager handles two processes simultaneously. It continously injects samples into your HPLC / UPLC unit and in parallel collects the next samples from the running test at designated timepoints. To avoid degradation of buffered samples, powerful cooling is optionally available.

Carry-over? Prevented.

Using a special cleaning routine, the ATS XtendTM flushes the injection loop of your HPLC / UPLC before the next sample is injected - preventing cross-contamination and carry-over. Once a test is completed, the operator can conveniently clean all sampling lines by activating a cleaning routine in the EasyTouchTM user interface.

Individual video monitoring of each dissolution vessel throughout the test

Advanced monitoring.

You can protocol individual vessel temperatures in all 6-8 vessels using the AutoLiftTM - before test start, when taking samples, or at any point during the test. To document that proper procedure has been followed, or more importantly, that a deviation has occurred, CenterViewTM video monitoring records the dissolution process individually per vessel.

Modules

AT dissolution bath for manual and semi-automated testing.

AT dissolution tester

Xtend™ dissolution bath with flexible sampling & monitoring functions.

Benchtop pump with maintenance-free ceramic piston heads

CP piston pump

Fast and powerful to push through filters and to handle foaming media.

System to collect and buffer dissolution samples and to sequentially inject them into a liquid chromatography system.

SAM SR sample manager

Automatically inject collected samples into a HPLC / UPLC system.

Direct injection of samples into HPLC / UPLC

HPLC / UPLC

Liquid chromatography system for analysis of samples.

WinSOTAX®plus

Dissolution software to manage methods, results, and reports.

Options

Benchtop filter station to automatically change syringe filters.

FS filter station

Automated change of syringe filters for multi-timepoint methods (DR/MR).

MPS media preparation station for manual and semi-automated dissolution testing systems.

MPS media station

Mobile media preparation station to heat, degas and dispense in vessels.

DVC-24 vessel cleaner

Mobile unit to empty and clean vessels of multiple dissolution testers.

Data management software for all methods, results, and users.

q-doc® software

All your data in one place with built-in 21 CFR part 11 compliance.

Integrated video monitoring for individual vessels.

CenterView™

Video monitoring of the dissolution process in each individual vessel.

Downloads

Downloads

Links