ATS Xtend™ LC On-/Offline

Automated injection of collected dissolution samples directly into your HPLC / UPLC system.

  • INJECTION - Unattended injection of dissolution samples directly into your liquid chromatography system
  • ERROR PREVENTION - No more time-consuming and error-prone manual re-racking of collected samples
  • TIME - Reduce the time from sampling to injection of filtered samples to an absolute minimum
  • COOLING - Prevent degradation of samples during buffering by adding cooling to your sample manager
  • FILTRATION - Use fine filtration down to 0.2 microns to prevent clogging of your HPLC / UPLC columns
  • INTEGRATION - Flexible integration of different HPLC / UPLC brands and systems possible
  • AUTOMATED - Highly repeatable sampling, filtration, and injection into HPLC / UPLC


Dissolution process steps with a semi-automated LC On-/Offline dissolution testing system.


Automated injection.

Forget about the problems associated with re-racking and manual transfer of dissolution samples. Your XtendTM dissolution system automatically takes samples from all vessels, filters down to a porosity of 0.2 microns, collects filtered samples in the SAM sample manager, and then immediately starts injecting them one by one directly into your HPLC / UPLC chromatography unit.

Flexible filtration.

The ATS XtendTM allows using a wide range of different filters - from tip filters / cannula filters for pre-filtration, to disc filters inside the suction head, and standard 25mm syringe filters. Avoid saturation or clogging for your DR / MR methods and automatically change filters with an integrated filter station.

Parallel processing.

For multi-timepoint tests with delayed release (DR) and modified release (MR) methods, the SAM sample manager handles two processes simultaneously. It continously injects samples into your HPLC / UPLC unit and in parallel collects the next samples from the running test at designated timepoints. To avoid degradation of buffered samples, powerful cooling is optionally available.

Carry-over? Prevented.

Using a special cleaning routine, the ATS XtendTM flushes the injection loop of your HPLC / UPLC before the next sample is injected - preventing cross-contamination and carry-over. Once a test is completed, the operator can conveniently clean all sampling lines by activating a cleaning routine in the EasyTouchTM user interface.

Individual video monitoring of each dissolution vessel throughout the test

Advanced monitoring.

You can protocol individual vessel temperatures in all 6-8 vessels using the AutoLiftTM - before test start, when taking samples, or at any point during the test. To document that proper procedure has been followed, or more importantly, that a deviation has occurred, CenterViewTM video monitoring records the dissolution process individually per vessel.


AT dissolution tester

Xtend™ dissolution bath with flexible sampling & monitoring functions.

CP piston pump

Fast and powerful to push through filters and to handle foaming media.

SAM SR sample manager

Automatically inject collected samples into a HPLC / UPLC system.


Liquid chromatography system for analysis of samples.


Dissolution software to manage methods, results, and reports.


FS filter station

Automated change of syringe filters for multi-timepoint methods (DR/MR).

MPS media station

Mobile media preparation station to heat, degas and dispense in vessels.

DVC-24 vessel cleaner

Mobile unit to empty and clean vessels of multiple dissolution testers.

q-doc® software

All your data in one place with built-in 21 CFR part 11 compliance.


Video monitoring of the dissolution process in each individual vessel.