Dissolution Testing USP 1/2/5/6

Dissolution is a test used by the Pharmaceutical industry to characterize the dissolution properties of the active drug, the active drug's release, and the dissolution from a dosage formulation. Different testing methods are described in USP, Ph.Eur., and other internationally harmonized Pharmacopeia as well as in FDA guidelines. Whereas standard tablets are typically tested according to the paddle method (USP 2), swelling or floating dosage forms such as capsules are tested using the basket method (USP 1). Paddle-over-disk (USP 5) and rotating cylinder (USP 6) methods are used for transdermal dosage forms.

100% unattended execution of multiple dissolution tests - from media preparation to self-cleaning of the entire system between test runs. Available in different analytical configurations for offline collection of samples, online UV-Vis measuring for immediate dissolution results, and direct injection into HPLC systems.

Dissolution Experts.

From the world's first fully automated self-cleaning dissolution system more than 25 years ago to pioneering release testing of novel dosage forms, SOTAX is driving innovation since 1973. Today, thousands of SOTAX instruments are in daily operation at Pharmaceutical companies all over the world.

Xtend™ Dissolution.

Whether you perform routine testing in QC or need to execute DOE studies in R&D – SOTAX systems allow flexible automation of your dissolution tests as needed. Standardized Xtend™ Modules can be combined to differently automated systems – making method transfer and scale-up easier than ever. From manual baths to full end-to-end automation with self-cleaning systems, Xtend™ is one platform for all your dissolution needs.

 

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