ATS Xtend™ LC On-/Offline

Automated injection from your dissolution tester of collected samples directly into your HPLC / UPLC system.

Semi automated dissolution tester USP 1256 ATS Xtend LC On-/Offline
  • INJECTION - Unattended injection of dissolution samples directly into your liquid chromatography system
  • ERROR PREVENTION - No more time-consuming and error-prone manual re-racking of collected samples
  • TIME - Reduce the time from sampling to injection of filtered samples to an absolute minimum
  • COOLING - Prevent degradation of samples during buffering by adding cooling to your sample manager
  • FILTRATION - Use fine filtration down to 0.2 microns to prevent clogging of your HPLC / UPLC columns
  • INTEGRATION - Flexible integration of different HPLC / UPLC brands and systems possible with your dissolution tester
  • AUTOMATED - Highly repeatable sampling, filtration, and injection into HPLC / UPLC


Dissolution process steps with a semi-automated LC On-/Offline dissolution testing system.


Automated injection.

Forget about the problems associated with re-racking and manual transfer of dissolution samples. Your XtendTM dissolution tester automatically takes samples from all vessels, filters down to a porosity of 0.2 microns, collects filtered samples in the SAM sample manager, and then immediately starts injecting them one by one directly into your HPLC / UPLC chromatography unit.

The FS filter station automatically performs filter changes on 6-8 channels simultaneously during dissolution tests.

Flexible filtration.

The ATS XtendTM allows using a wide range of different filters - from tip filters / cannula filters for pre-filtration, to disc filters inside the suction head, and standard 25mm syringe filters. Avoid saturation or clogging for your DR / MR methods and automatically change filters with an integrated filter station.

Samples in rack for dissolution tester

Parallel processing.

For multi-timepoint tests with delayed release (DR) and modified release (MR) methods, the SAM sample manager handles two processes simultaneously. It continously injects samples into your HPLC / UPLC unit and in parallel collects the next samples from the running test at designated timepoints. To avoid degradation of buffered samples, powerful cooling is optionally available.

Multi-purpose media selector perform one-touch sample line cleaning on completion of a test.

Carry-over? Prevented.

Using a special cleaning routine, the ATS XtendTM flushes the injection loop of your HPLC / UPLC before the next sample is injected - preventing cross-contamination and carry-over. Once a test is completed, the operator can conveniently clean all sampling lines by activating a cleaning routine in the EasyTouchTM user interface.

Individual video monitoring of each dissolution tester vessel throughout the test.

Advanced monitoring.

You can protocol individual vessel temperatures in all 6-8 vessels using the AutoLiftTM - before test start, when taking samples, or at any point during the test. To document that proper procedure has been followed, or more importantly, that a deviation has occurred, CenterViewTM video monitoring records the dissolution process individually per vessel.


AT dissolution tester bath for manual and semi-automated testing.

AT dissolution tester

Xtend™ dissolution bath with flexible sampling & monitoring functions.

Benchtop pump with maintenance-free ceramic piston heads for dissolution tester USP 1256.

CP piston pump

Fast and powerful to push through filters and to handle foaming media.

SAM Sample Manager SR to collect and buffer dissolution testing samples and to sequentially inject them into a liquid chromatography system from 15 timepoints..

SAM SR sample manager

Automatically inject collected samples into a HPLC / UPLC system.

Direct injection of dissolution testing samples into HPLC / UPLC.


Liquid chromatography system for analysis of samples.

WinsotaxPlus Dissolution testing software 21 CFR Part 11 compliant, controlling all aspects of data capture and analysis with customized reporting and exporting.


Dissolution software to manage methods, results, and reports.


Benchtop filter station to automatically change syringe filters for dissolution tester USP 1256.

FS filter station

Automated change of syringe filters for multi-timepoint methods (DR/MR).

MPS media preparation station for manual and semi-automated dissolution testing systems.

MPS media station

Mobile media preparation station to heat, degas and dispense in vessels.

Data management software for all methods, results, and users.

q-doc® software

All your data in one place with built-in 21 CFR part 11 compliance.

Video monitoring of the dissolution process in each individual vessel.


Video monitoring of the dissolution process in each individual vessel.